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The available engine options for the VUE are:
- 3.6L (VIN 7, 8th digit, opt LY7)
- 3.5L (VIN N, 8th digit, opt LZ4)
- 2.4L VIN P, 8th digit (opt LE5)
- 2.4L VIN Z, 8th digit (opt LAT)
- A.T. 3.0L (opt L81) FWD (M09)
- A.T. 3.0L (opt L81) AWD (M45)
- A.T. 2.2L (opt L61) FWD (M75)
- A.T. 2.2L (opt L61) AWD (opt M16)
- 3.5L (VIN 4, opt L66)
- 2.4L (VIN Z, 8th digit, opt LAT)
- 2.2L (VIN D, 8th digit, opt L61)
- A.T. 3.5L (opt L66) FWD (MJ7)
- A.T. 3.5L (opt L66) AWD (MJ8)
- A.T. 2.2L (opt L61) FWD (MN5)
- 3.5L (VIN 4, 8th digit, opt L66)
- 2.2L (VIN D, 8th digit, opt L61) exhaust manifold is not drilled & tapped for AIR check valve w/o EGR port in head
- 2.2L (VIN D, 8th digit, opt L61) exhaust manifold is not drilled & tapped for AIR check valve EGR port in head
- 2.2L (VIN D, 8th digit, opt L61) exhaust manifold is drilled & tapped for AIR check valve w/o EGR port in head
- 2.2L (VIN D, 8th digit, opt L61) exhaust manifold is drilled & tapped for AIR check valve EGR port in head
- M.T. (4 cyl)
- 3.0L (VIN B, 8th digit, opt L81) FWD
- 3.0L (VIN B, 8th digit, opt L81) AWD
- 2.2L (VIN D, 8th digit, opt L61) exhaust manifold is not drilled & tapped for AIR check valve
- 2.2L (VIN D, 8th digit, opt L61) exhaust manifold is drilled & tapped for AIR check valve
- 3.6L VIN 7, 8th digit (opt LY7)
- 3.6L VIN B, 8th digit (opt LCS)
- A.T. 2.2L (opt L61) FWD
- A.T. 2.2L (opt L61) AWD
- M.T. (4 cyl) from VIN 3S903336
- M.T. (4 cyl) thru VIN 3S903335
- A.T. 2.2L (opt L61)
- A.T. 3.5L FWD (MJ7)
- A.T. 3.5L AWD (MJ8)
- A.T. 2.4L (opt LAT)
- A.T. XR FWD (opt MH2) from 10/08/08
- A.T. XR FWD (opt MH2) thru 10/07/08
- A.T. XR AWD (opt MH4) from 10/08/08
- A.T. XR AWD (opt MH4) thru 10/07/08
- A.T. XE FWD (MN5) from 1/07-08 (ID 8EMJ)
- A.T. XE FWD (MN5) thru 1/06/08 (ID 8ELJ)
- A.T. XE AWD (opt MH4) from 10/08/08
- A.T. XE AWD (opt MH4) thru 10/07/08
- A.T. Red Line FWD (opt MH2) from 10/08/08
- A.T. Red Line FWD (opt MH2) thru 10/07/08
- A.T. Red Line AWD (opt MH4) from 10/08/08
- A.T. Red Line AWD (opt MH4) thru 10/07/08
- A.T. Green Line (Hybrid) from 1/07/08
- A.T. Green Line (Hybrid) thru 1/06/08
- A.T. 3.6L VIN 7, 8th digit, (opt LY7) FWD
- A.T. 3.6L VIN 7, 8th digit, (opt LY7) AWD
- A.T. 3.6L VIN B, 8th digit, (opt LCS)
- A.T. 3.5L
- A.T. 2.4L VIN Z, 8th digit, (opt LAT)
- A.T. 2.4L VIN P, 8th digit, (opt LE5)

